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Related Experiment Video

Updated: May 31, 2026

Assessing Activity-based Anorexia in Mice

Assessing Activity-based Anorexia in Mice

Published on: May 14, 2018

Suicide attempts in anorexia nervosa subtypes.

Laura Forcano¹, Eva Alvarez, Juan J Santamaría

¹Ciber Fisiopatologia Obesidad y Nutrición, Instituto Salud Carlos III, Barcelona, Spain.

Comprehensive Psychiatry

|June 21, 2011

Summary

Women with anorexia nervosa (AN) have an increased risk of suicide attempts. Purging behaviors and depression symptoms in AN heighten suicidality concerns, while anxiety may indicate higher risk in restricting AN.

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Area of Science:

Psychiatry
Clinical Psychology
Eating Disorders Research

Background:

Anorexia nervosa (AN) is associated with a significantly elevated risk for suicide attempts.
Understanding the interplay between personality traits, psychopathology, and suicidality in AN is crucial for effective clinical intervention.

Purpose of the Study:

To investigate the prevalence of lifetime suicide attempts in women diagnosed with anorexia nervosa.
To compare individuals with AN who have attempted suicide versus those who have not, across eating disorder symptoms, general psychopathology, and personality profiles.
To examine these factors in relation to a healthy control group and across different subtypes of AN.

Main Methods:

A study involving 104 outpatients with restricting anorexia nervosa, 68 outpatients with purging anorexia nervosa, and 146 healthy comparison individuals.
Assessment of eating disorder symptoms, general psychopathology, and personality traits.

Main Results:

Suicide attempt prevalence varied significantly across groups: 0% in controls, 8.65% in restricting AN, and 25.0% in purging AN (P = .003).
Individuals with a history of suicide attempts exhibited elevated depression measures.
Within the restricting AN group, those who attempted suicide showed significantly higher scores for Phobic Anxiety (P = .001).

Conclusions:

The presence of purging behaviors and depressive symptoms in individuals with AN warrants increased clinical vigilance for suicidality.
Elevated anxiety levels in restricting AN may serve as an indicator of heightened suicide risk.