Vitiligo in a patient receiving infliximab for refractory ulcerative colitis
Waleed A Ismail1, Saleh A Al-Enzy, Saqer A Alsurayei
1Department of Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt. waleed.fattah@yahoo.com
Abstract:
Infliximab is a chimerical monoclonal antibody that inhibits pro-inflammatory activity of tumour-necrosis factor alpha (TNFα) and it is the primary biological agent used in the treatment of moderate-to-severe ulcerative colitis (UC). We report a case of vitiligo following infliximab administration in a patient with refractory UC. The case serves as a reminder of adverse cutaneous reactions induced by TNFα-antagonist therapy.
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