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Related Experiment Video

Updated: May 31, 2026

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Predictors of neck bleeding after eversion carotid endarterectomy.

Claudio Baracchini1, Mario Gruppo, Franco Mazzalai

  • 1Department of Neurological Sciences, University of Padua, School of Medicine, Padova, Italy.

Journal of Vascular Surgery
|June 21, 2011
PubMed
Summary

Neck bleeding after carotid endarterectomy (CEA) is common, with clopidogrel use and hypertension being key risk factors. Continuing antiplatelet therapy before surgery increases bleeding risk, but it does not raise stroke or death rates.

Related Experiment Videos

Last Updated: May 31, 2026

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Area of Science:

  • Vascular Surgery
  • Cardiovascular Medicine
  • Surgical Complications

Background:

  • Eversion carotid endarterectomy (eCEA) is a procedure to prevent stroke.
  • Neck bleeding is a potential complication following eCEA.
  • Identifying predictors of neck bleeding is crucial for patient safety.

Purpose of the Study:

  • To identify predictors of neck bleeding after eversion carotid endarterectomy (eCEA).
  • To assess the association between preoperative antiplatelet therapy and neck bleeding.
  • To determine the impact of postoperative hypertension on neck bleeding risk.

Main Methods:

  • Analysis of a prospectively compiled database of primary eCEAs (1998-2009).
  • Univariate analysis to identify predictors of neck bleeding.
  • Endpoint defined as any neck bleeding post-eCEA, including cases requiring re-exploration.

Main Results:

  • Neck bleeding occurred in 8.2% of 1458 eCEAs; 4.7% required re-exploration.
  • Preoperative clopidogrel, especially when continued to the day before surgery, was a significant risk factor (OR 3.84).
  • Postoperative hypertension was a major predictor for general neck bleeding (OR 9.44) and re-exploration (OR 15.27).
  • Other antiplatelet agents (aspirin, ticlopidine) increased bleeding risk only if continued perioperatively.

Conclusions:

  • Neck bleeding after eCEA is relatively common but not associated with increased stroke or death risk.
  • Preoperative clopidogrel use and postoperative hypertension are significant risk factors for neck bleeding requiring re-exploration.
  • Further research is needed to validate these findings and develop preventative strategies.