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Updated: May 31, 2026
Study of the Functions and Activities of Neuronal K-Cl Co-Transporter KCC2 Using Western Blotting
Published on: December 9, 2022
Ketogenic diet does not change NKCC1 and KCC2 expression in rat hippocampus
Gisela Gómez-Lira1, Julieta Griselda Mendoza-Torreblanca, Leticia Granados-Rojas
1Laboratorio de Neuromorfometría, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Del. Coyoacán, México D.F. 04530, México. ggomez@fisio.cinvestav.mx
Abstract:
In control rats, we examined the effects of ketogenic diet on NKCC1 and KCC2 expression levels in hippocampus. Neither the number of NKCC1 immunoreactive cells nor the intensity of labeling of KCC2 was found to modify in hippocampus of the rats after ketogenic diet treatment. These results indicate that ketogenic diet by itself does not modify the expression of these cation chloride cotransporters.
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