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Tissue-specific gene targeting by the multiprotein mammalian DREAM complex.

Stephen Flowers1, George R Beck, Elizabeth Moran

  • 1Department of Orthopaedics, New Jersey Medical School-University Hospital Cancer Center, University of Medicine and Dentistry, New Jersey, Newark, New Jersey 07103, USA.

The Journal of Biological Chemistry
|June 21, 2011
PubMed
Summary

The DREAM complex, including p130 and E2F4, typically represses genes in growth arrest. New research shows it also acts in proliferating cells, linking cell cycle control to tissue differentiation.

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