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Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding
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Published on: August 22, 2016

Crowding is size and eccentricity dependent.

Rick Gurnsey1, Gabrielle Roddy, Waël Chanab

  • 1Department of Psychology, Concordia University, Montreal, Quebec, Canada. rick.gurnsey@concordia.ca

Journal of Vision
|June 21, 2011
PubMed
Summary
This summary is machine-generated.

Crowding, where surrounding items hinder target perception, intensifies with visual field eccentricity. This study reveals crowding is absent at fixation but significant in peripheral vision, challenging prior assumptions.

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Area of Science:

  • Visual perception
  • Neuroscience
  • Psychophysics

Background:

  • Crowding describes lateral interactions where flanking stimuli impede target detection or discrimination.
  • It is widely assumed that crowding is exclusive to peripheral vision, with no occurrence at fixation.

Purpose of the Study:

  • To investigate the presence and nature of crowding across different visual field eccentricities.
  • To determine if crowding interactions change with increasing distance from the fovea.

Main Methods:

  • Three psychophysical tasks were employed to measure target size and flanker separation at threshold.
  • Measurements were taken at eccentricities from 0° to 16° in the lower visual field.
  • A double-scaling procedure was used to analyze the psychometric functions.

Main Results:

  • The magnitude of crowding significantly increased with eccentricity, from no crowding at fixation to extreme crowding at 16°.
  • Data from all tasks, when scaled, exhibited a consistent psychometric function across eccentricities.
  • This suggests a unified mechanism underlying crowding, with parameters varying by eccentricity.

Conclusions:

  • Crowding is not limited to the periphery and its magnitude is strongly dependent on eccentricity.
  • The findings support a model where size-dependent target responses and distance-dependent flanker interference interact.
  • The interference from flankers appears to escalate with increasing eccentricity in the visual field.