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Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
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Acute liver failure due to acute fatty liver of pregnancy

S Wand1, R M Waeschle, N Von Ahsen

  • 1Department of Anesthesiology, Emergency and Intensive Care Medicine, University Hospital Goettingen, Germany. saskia.wand@med.uni-goettingen.de

Minerva Anestesiologica
|June 21, 2011
PubMed

Acute fatty liver of pregnancy (AFLP) is a rare but serious liver disease and typically occurs during the third trimester. It carries the risk for significant perinatal and maternal mortality. Therefore an early diagnosis and delivery, followed by close monitoring and optimized management of the impaired liver function with all associated problems are necessary to prevent maternal and foetal death. This case report focuses on the management of acute liver failure due to AFLP in a 31 year old women treated in our intensive care unit (ICU) after an emergency C-section.

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