Related Experiment Video
Updated: May 31, 2026
10:21
Cell Based Assays of SINEUP Non-coding RNAs That Can Specifically Enhance mRNA Translation
Published on: February 1, 2019
Small RNAs hit a new target: Modulation of gene expression by targeting the non-coding sequences downstream from a
1Global Prior Art, Inc.; Boston, MA USA.
Artificial DNA, PNA & XNA
|June 21, 2011
Abstract:
The University of Texas researchers have recently discovered that small synthetic RNAs (sRNAs) that are complementary to sequences located 3'-outside of genes can efficiently modulate gene expression. These new findings significantly expand the transcription-regulatory potential of sRNAs, and they also may provide useful leads for other artificial nucleobase oligomers to target sequences beyond the 3' termini of mRNA.
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Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
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