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Updated: May 31, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Primary neuroendocrine neoplasm of the gallbladder
Venkatesh Kanakala1, Ramesh Kasaraneni, David A Smith
1North Tyneside General Hospital, General Surgery, Rake Lane, North Shields, Newcastle Upon Tyne NE29 8NH, UK.
A rare neuroendocrine tumour of the gallbladder was incidentally discovered during surgery for gallstones. This primary gallbladder neuroendocrine tumour had no signs of metastasis and the patient recovered well post-operation.
Area of Science:
- Gastroenterology and Hepatobiliary Surgery
- Oncology
- Surgical Pathology
Background:
- Neuroendocrine tumours (NETs) commonly originate in the gastrointestinal tract or bronchopulmonary system.
- Gallbladder NETs are exceptionally rare, with only 42 cases documented.
- This study presents a case of an incidental gallbladder NET.
Purpose of the Study:
- To report a rare case of a primary neuroendocrine tumour of the gallbladder.
- To highlight the incidental nature of diagnosis in routine histopathology.
- To discuss the clinical and pathological characteristics of this rare entity.
Main Methods:
- Laparoscopic cholecystectomy for symptomatic cholelithiasis.
- Routine histopathological examination of the resected gallbladder.
- Post-operative investigations to rule out concurrent lesions or metastases.
Main Results:
- An incidental primary neuroendocrine tumour of the gallbladder was identified.
- The patient experienced an uncomplicated recovery from surgery.
- No concurrent lesions or distant metastases were detected.
Conclusions:
- Primary neuroendocrine tumours of the gallbladder are exceedingly rare.
- Histopathological examination is crucial for diagnosing incidental findings.
- Complete surgical resection and follow-up are essential for managing gallbladder NETs.
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