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05:26
Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
Published on: March 1, 2024
Congenital candidiasis presenting as septic shock without rash
Kathryn Browning Carmo1, Nick Evans, David Isaacs
1Newborn Care and University of Sydney, Sydney, Australia.
BMJ Case Reports
|June 21, 2011
Summary
Congenital candidiasis, a rare fungal infection, can present differently in premature twins. One twin survived with a rash, while the other succumbed to severe sepsis.
Area of Science:
- Neonatal Medicine
- Infectious Diseases
- Fungal Infections
Background:
- Congenital candidiasis is a rare condition, typically presenting with a benign course.
- Premature infants are at increased risk for severe infections.
Purpose of the Study:
- To report a case of congenital candidiasis with disparate outcomes in twins.
- To highlight the variable clinical spectrum of this infection in neonates.
Main Methods:
- Case report of premature twins (32 weeks gestation) diagnosed with congenital candidiasis.
- Clinical observation of disease progression and outcomes.
Main Results:
- One twin presented with neutropenia and died from sepsis and septic shock within 22 hours.
- The second twin developed a delayed rash but remained well and survived.
Conclusions:
- Congenital candidiasis can have vastly different prognoses, even in genetically identical twins.
- Early recognition and management are crucial for improving outcomes in affected neonates.
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