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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...

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Related Experiment Video

Updated: May 31, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Clostridium difficile enteritis in a patient after total proctocolectomy.

Oliver Peacock1, William Speake, Aidan Shaw

  • 1Derby City General Hospital, Uttoxeter Road, Derby, Derbyshire, DE22 3NE, UK.

BMJ Case Reports
|June 21, 2011
PubMed
Summary
This summary is machine-generated.

Clostridium difficile enteritis is a rare complication, often seen after antibiotic use and major colon surgery. Early recognition and aggressive treatment in patients with ileostomy flux or diarrhea are crucial to reduce mortality.

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Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
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Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
08:20

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Published on: July 12, 2018

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Surgical Pathology

Background:

  • Clostridium difficile infection (CDI) typically affects the colonic mucosa.
  • CDI is rarely reported as a cause of enteritis.
  • Previous antibiotic therapy is a common risk factor for CDI.

Purpose of the Study:

  • To describe a case of Clostridium difficile enteritis in a patient with a history of panproctocolectomy and end ileostomy.
  • To review previously reported cases of Clostridium difficile enteritis.
  • To highlight the importance of considering CDI in patients with ileostomy-related diarrhea post-colonic surgery.

Main Methods:

  • Case report of a 30-year-old female patient with Clostridium difficile enteritis.
  • Review of existing literature on Clostridium difficile enteritis.
  • Analysis of predisposing factors including antibiotic use and major colonic resection.

Main Results:

  • The patient presented with Clostridium difficile enteritis following panproctocolectomy and end ileostomy.
  • All previously reported cases of Clostridium difficile enteritis involved prior antibiotic therapy.
  • Major colonic resection was identified as a precipitating factor in these cases.

Conclusions:

  • Small bowel Clostridium difficile infection should be suspected in patients experiencing ileostomy flux or diarrhea after extensive colonic surgery.
  • Prompt diagnosis and aggressive management of Clostridium difficile enteritis can potentially decrease its high mortality rate.
  • Understanding the association between antibiotic use, colonic resection, and enteritis is vital for patient outcomes.