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Related Experiment Video

Updated: May 31, 2026

Neonatal Pial Surface Electroporation
06:22

Neonatal Pial Surface Electroporation

Published on: May 7, 2014

Herpetic neonatal pustular rash.

Manjula Meda1, Charles Godden, Dianne Irish

  • 1St. George's Hospital, Microbiology, Blackshaw Road, Tooting, London, SW17 0QT, UK.

BMJ Case Reports
|June 21, 2011
PubMed
Summary
This summary is machine-generated.

Neonatal pustular rash, often linked to staphylococcal infections, can also stem from herpes simplex virus. Early diagnosis and prompt antiviral treatment are crucial for saving lives in affected newborns.

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Published on: August 12, 2020

Area of Science:

  • Neonatal dermatology
  • Pediatric infectious diseases
  • Viral infections in newborns

Background:

  • Pustular rash is a common neonatal presentation, frequently attributed to bacterial infections like Staphylococcus.
  • Herpes simplex virus (HSV) can manifest as a pustular rash in neonates, mimicking bacterial causes.
  • Accurate diagnosis is critical as HSV infections can lead to severe morbidity and mortality.

Purpose of the Study:

  • To highlight a case of neonatal pustular rash caused by herpes simplex virus.
  • To emphasize the importance of considering viral etiologies in neonatal pustular eruptions.
  • To underscore the necessity of prompt antiviral therapy in suspected cases.

Main Methods:

  • Case report of a 12-day-old neonate presenting with a pustular rash.
  • Clinical evaluation including diagnostic sample collection.
  • Review of differential diagnoses for neonatal pustular rash, considering bacterial and viral pathogens.

Main Results:

  • Bacterial cultures were negative, prompting further investigation.
  • Herpes simplex virus infection was identified as the cause of the pustular rash.
  • The neonate's condition required specific antiviral management.

Conclusions:

  • Neonatal pustular rash necessitates a high index of suspicion for herpes simplex virus, particularly with negative bacterial cultures.
  • Early recognition and initiation of antiviral treatment (aciclovir) are vital for improving outcomes.
  • Timely diagnosis and intervention can be life-saving in neonatal herpes simplex virus infections.