Related Experiment Video
Updated: May 31, 2026

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury
Published on: February 10, 2026
An unusual case of acute on chronic renal failure following percutaneous coronary intervention
Stasinos Theodorou1, Peter Glennon
1University Hospital of Coventry and Warwickshire, Cardiology, Clifford Bridge Road, Coventry CV2 2DX, UK.
Abstract:
Contrast nephrotoxicity is a common and well-documented complication of procedures utilising x ray contrast medium. It should be looked for whenever patients are exposed to contrast medium as it carries a good prognosis if managed appropriately, with only a minority of cases requiring dialysis. It is essential, however, that other causes of renal dysfunction are excluded before making a firm diagnosis of contrast nephropathy. Any delay in administering the appropriate treatment depending on the underlying pathology can result in devastating consequences. The differential diagnosis of acute renal failure is extensive and a systematic diagnostic approach should always be observed.
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