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Updated: May 31, 2026

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Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
Published on: June 2, 2019
Diabetic muscle infarction
Antony Mathew1, Sreenath Reddy, Colin Archibald
1University Hospital of Wales, Cardiff, UK.
BMJ Case Reports
|June 21, 2011
Summary
Diabetic muscle infarction (DMI) is a rare complication of diabetes. This case highlights the need for high suspicion in diabetic patients presenting with limb pain, as DMI has a poor long-term prognosis.
Area of Science:
- Endocrinology
- Diabetology
- Musculoskeletal Medicine
Background:
- Diabetic muscle infarction (DMI) is a rare complication of poorly controlled, long-standing diabetes mellitus.
- Few cases are documented, making its pathophysiology unclear and diagnosis challenging.
Purpose of the Study:
- To describe a case of DMI in a young adult with type 2 diabetes mellitus.
- To emphasize the diagnostic utility of MRI in DMI.
- To discuss the clinical implications and prognosis of DMI.
Main Methods:
- Case report of a 34-year-old male with type 2 diabetes.
- Clinical presentation of sudden onset left thigh pain.
- Diagnostic Magnetic Resonance Imaging (MRI) findings.
Main Results:
- The patient was diagnosed with DMI.
- MRI findings were characteristic and diagnostic for DMI.
- Management was symptomatic, with a good short-term prognosis but high recurrence rate.
Conclusions:
- DMI requires a high index of suspicion in diabetic patients with non-traumatic limb pain.
- While short-term prognosis is favorable, long-term outcomes are poor due to associated cardiovascular complications.
- Further research into DMI pathophysiology and management is warranted.
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