Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Prosopagnosia01:24

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic histories of individuals from multi-faith medieval Sicily.

PloS one·2026
Same author

Asynchronous Remote Clinic Telemedicine for the Monitoring of Keratoconus: Patient Perspectives.

Cornea·2026
Same author

Toward universal dose prediction: A multi-scale, multi-objective framework for sequential boost radiotherapy.

Medical physics·2026
Same author

Regional and temporal trends in antimicrobial susceptibility among isolates from bacterial keratitis: a systematic review and meta-analysis.

The Lancet. Microbe·2026
Same author

RAPID-LC: rapid evidence-to-practice uptake of large core thrombectomy across a stroke consortium.

Journal of neurology·2026
Same author

Performance of an Artificial Intelligence Foundation Model for Prostate Radiotherapy Segmentation.

JCO clinical cancer informatics·2026
Same journal

Early onset cerebral oedema in adult diabetic ketoacidosis with complete resolution.

BMJ case reports·2026
Same journal

Third salvage haematopoietic stem cell transplantation in a child with very early-onset IBD due to interleukin-10 receptor deficiency.

BMJ case reports·2026
Same journal

Fungal keratitis caused by <i>Trichomonascus ciferrii</i> in an immunocompetent adult.

BMJ case reports·2026
Same journal

An unusual cause of acute small bowel obstruction in a child: multiple trichobezoars diagnosed on CT.

BMJ case reports·2026
Same journal

Massive haemoptysis secondary to pulmonary artery aneurysms in Hughes-Stovin syndrome: a variant of Behçet's disease managed with immunosuppression and endovascular embolisation.

BMJ case reports·2026
Same journal

The blue dilemma: a rare presentation of dual hemoglobinopathy in a pregnant patient.

BMJ case reports·2026
See all related articles

Related Experiment Video

Updated: May 31, 2026

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse
10:52

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse

Published on: April 7, 2014

Keratoconus associated with CSNB1.

Dan Nguyen1, Chris Hemmerdinger, Richard Hagan

  • 1Bristol Eye Hospital, Lower Maudlin Street, Bristol, BS1 2LX, UK.

BMJ Case Reports
|June 21, 2011
PubMed
Summary
This summary is machine-generated.

This study reports a case of keratoconus, a corneal disease, co-occurring with congenital stationary night blindness (CSNB). The patient presented with severe visual impairment and characteristic corneal abnormalities, with no identified external causes.

Related Experiment Videos

Last Updated: May 31, 2026

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse
10:52

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse

Published on: April 7, 2014

Area of Science:

  • Ophthalmology
  • Genetics
  • Corneal Diseases
  • Neuro-ophthalmology

Background:

  • Keratoconus is a progressive corneal ectasia characterized by thinning, irregular astigmatism, and visual impairment.
  • Congenital Stationary Night Blindness (CSNB) is a group of inherited retinal disorders affecting night vision.
  • The co-occurrence of keratoconus and CSNB is rare, with limited established links between these conditions.

Purpose of the Study:

  • To document and analyze a rare case of coexisting keratoconus and congenital stationary night blindness (CSNB).
  • To investigate potential associations or genetic predispositions linking these two distinct conditions.
  • To highlight the clinical presentation and diagnostic findings in such a comorbid case.

Main Methods:

  • Clinical examination including best-corrected visual acuity (BCVA) assessment.
  • Ophthalmic imaging: corneal topography to evaluate corneal shape and thickness.
  • Diagnostic testing: Electroretinography (ERG) to assess retinal function.

Main Results:

  • The patient presented with significant visual acuity deficits and bilateral central corneal thinning, paracentral ectasia, and Vogt's striae.
  • Corneal topography revealed severe irregular astigmatism (7.4 diopters) and corneal thinning (335 μm).
  • Electroretinography (ERG) demonstrated a complete absence of retinal response, indicative of severe visual pathway dysfunction.

Conclusions:

  • The co-occurrence of keratoconus and CSNB in this patient may be coincidental, as no prior direct association has been established.
  • Both keratoconus and CSNB exhibit genetic components, suggesting a potential, though unproven, shared genetic predisposition.
  • Further research is warranted to explore any potential etiological or genetic links between keratoconus and CSNB.