Related Experiment Video
Updated: May 31, 2026
08:50
Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
Published on: October 18, 2024
Bariatric surgery does not cure all type 2 diabetes.
Khalid Ayub Jadoon1, Helen Anne Van der Wijngaart, Stephen A Olczak
1Pilgrim Hospital Boston, Diabetes and Endocrinology, Sibsey Road, Boston PE21 9QS, UK.
BMJ Case Reports
|June 21, 2011
Summary
Bariatric surgery can improve type 2 diabetes, but some patients may experience complications like diabetic ketoacidosis post-procedure. This case highlights the need for careful monitoring after gastric banding surgery.
Area of Science:
- Metabolic Surgery
- Endocrinology
- Bariatric Procedures
Background:
- Bariatric surgery is a common treatment for morbid obesity.
- Obesity is frequently associated with type 2 diabetes mellitus.
- Surgical interventions often lead to improvements in obesity-related comorbidities, including diabetes.
Purpose of the Study:
- To investigate the impact of bariatric surgery on type 2 diabetes.
- To report a case of diabetic ketoacidosis following gastric banding in a patient with type 2 diabetes.
Main Methods:
- Review of existing literature on bariatric surgery outcomes for type 2 diabetes.
- Case report detailing a patient's presentation and management post-gastric banding.
Main Results:
- Bariatric surgery, particularly gastric bypass, shows high efficacy in managing type 2 diabetes, with over 80% of patients achieving remission in one study.
- A case of severe diabetic ketoacidosis occurred 2 days post-operatively in a patient with insulin-treated type 2 diabetes who underwent gastric banding.
Conclusions:
- While bariatric surgery is effective for weight control and diabetes management, potential complications like diabetic ketoacidosis must be considered.
- Close post-operative monitoring is crucial for patients with diabetes undergoing bariatric procedures, including gastric banding.
Related Concept Videos
01:36Carbohydrate Metabolism
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...
01:22Diabetes Mellitus: Type 2 and Gestational
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
01:15Diabetes: Management and Pharmacotherapy
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
01:24Type II Diabetes II: Pathophysiology
PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
01:26Type II Diabetes I: Introduction
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
01:22Diabetes Mellitus: Overview and Type I Subtype
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...