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Updated: May 31, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Lymphatic system anomalies in Crouzon syndrome
Pierre Bourgeois1, Stéphane Moniotte
1Institute Jules Bordet, Service of Nuclear Medicine, 121, Boulevard De Waterloo, Brussels, B-1000, Belgium.
Abstract:
Crouzon syndrome is a rare genetic disorder characterised mainly by distinctive malformations of the skull and facial region and caused by mutations in the fibroblast growth factor receptor 2 (FGFR2) gene. No study reported on oedemas related to lymphatic system abnormalities in these patients. A case of Crouzon syndrome displaying classic facial anomalies but also with bilateral lower limb oedema is reported in whom lymphoscintigraphic investigation of the limbs clearly delineated the presence of lymphatic system anomalies.
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