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Updated: May 31, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

Bilateral ophthalmic artery occlusion.

Manuel Monteiro¹, Salgado Borges, Joaquim Cruz

¹Clinic of Ophthalmology, Antas, Porto and Faculdade das Ciências da Saúde, Beira Interior University, Covilhã, Portugal. Avª Fernão Magalhães 1989, 4350-171, Porto, Portugal.

BMJ Case Reports

|June 21, 2011

Summary

This case study highlights an elderly patient presenting with ocular ischemic syndrome symptoms and isolated stenosis in both ophthalmic arteries.

Area of Science:

Ophthalmology
Vascular Medicine

Background:

Ocular ischemic syndrome (OIS) is a severe condition often linked to carotid artery disease.
Ophthalmic artery stenosis is a known but less common cause of OIS.

Purpose of the Study:

To report an unusual case of OIS caused solely by bilateral ophthalmic artery stenosis.
To emphasize the importance of considering isolated ophthalmic artery stenosis in the differential diagnosis of OIS.

Main Methods:

Clinical case presentation.
Review of patient's medical history and diagnostic findings.

Main Results:

The patient exhibited classic symptoms of OIS.
Diagnostic imaging confirmed severe stenosis exclusively in both ophthalmic arteries, without significant carotid disease.

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A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

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Published on: November 12, 2020

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

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Published on: July 21, 2013

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

Conclusions:

Isolated bilateral ophthalmic artery stenosis can present as OIS.
This case underscores the need for comprehensive vascular assessment of the ophthalmic arteries in suspected OIS cases.