Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Transient Ischemic Attack l: Introduction

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...

Amnesia

Amnesia

Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...

Dissociative Amnesia

Dissociative Amnesia

Dissociative amnesia is a complex psychological condition that manifests as an inability to recall personal information, often tied to traumatic or stressful events. Unlike general amnesia, individuals with this condition retain the ability to perform routine activities and procedural tasks, such as operating a phone or navigating public transportation, yet experience profound gaps in autobiographical memory. These lapses may encompass significant life events, such as suicide attempts or...

Hepatic Encephalopathy

Hepatic Encephalopathy

DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...

Desensitization and Tachyphylaxis

Desensitization and Tachyphylaxis

Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
Several...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Targeted use of Prostaglandin E1 Therapy in "Duct-dependent" Congenital Diaphragmatic Hernia.

American journal of respiratory and critical care medicine·2026

Same author

Development of a novel split, frozen, thawed and washed red cell component for intrauterine transfusion.

Vox sanguinis·2026

Same author

Early left ventricular diastolic function and disease severity in congenital diaphragmatic hernia.

Pediatric research·2025

Same author

Serotonin reuptake inhibiting antidepressants: A trigger for visual snow syndrome?

The International journal of risk & safety in medicine·2025

Same author

Drug safety: The roles of big data and clinical experience.

Indian journal of medical ethics·2025

Same author

Artificial intelligence: Medical journalism and medical science.

The International journal of risk & safety in medicine·2025

Search research articles

Related Experiment Videos

Transient global amnesia associated with statin intake.

David Healy¹, Roger Morgan, Srinivasan Chinnaswamy

¹Cardiff University, Psychological Medicine, Hergest Unit, Bangor, LL57 2PW, U K.

BMJ Case Reports

|June 21, 2011

Summary

A patient experienced memory problems and suicidal concerns after starting rosuvastatin, a statin medication. Symptoms resolved upon discontinuing the drug, suggesting a potential link between statin use and cognitive side effects.

Related Experiment Videos

Area of Science:

Neuroscience
Pharmacology
Clinical Medicine

Background:

Statins are widely prescribed cholesterol-lowering drugs.
Adverse cognitive effects associated with statin therapy are occasionally reported.
Differentiating drug-induced cognitive changes from other neurological or psychiatric conditions is clinically important.

Purpose of the Study:

To report a case of significant amnestic symptoms potentially linked to rosuvastatin use.
To highlight the importance of considering medication side effects in patients presenting with cognitive decline.

Main Methods:

Case report of a 57-year-old male patient.
Detailed clinical observation of cognitive symptoms.
Assessment of symptom changes following medication initiation and discontinuation.

Main Results:

The patient developed diverse amnestic features after initiating rosuvastatin.
No overt signs of depression were noted despite concerns of suicidal ideation.
Cognitive symptoms resolved completely after discontinuing rosuvastatin.

Conclusions:

Rosuvastatin may be associated with reversible amnestic syndrome.
Thorough medication review is crucial in patients with unexplained cognitive and mood symptoms.
Further research into statin-induced cognitive dysfunction is warranted.