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Updated: May 31, 2026

Intratracheal Instillation of Stem Cells in Term Neonatal Rats

Intratracheal Instillation of Stem Cells in Term Neonatal Rats

Published on: May 4, 2020

Rickets and tracheobronchomalacia.

Harish Bangalore¹, Suniti Bisht, Baba Inusa

¹Evelina Children's Hospital, Paediatrics, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.

BMJ Case Reports

|June 21, 2011

Summary

Rickets, a bone-weakening disease, is increasingly common. This case highlights severe respiratory issues in rickets, suggesting tracheobronchomalacia may be an under-recognized complication requiring further study.

Area of Science:

Pediatrics
Pulmonology
Endocrinology

Background:

Rickets incidence is rising globally, even in developed nations.
Respiratory infections are a known comorbidity of rickets.
Severe respiratory complications in rickets warrant investigation.

Purpose of the Study:

To report a case of rickets with significant respiratory compromise.
To identify potential underlying causes for respiratory distress in rickets.
To explore tracheobronchomalacia as a possible association with rickets.

Main Methods:

Case report presentation.
Clinical assessment of a child with rickets and respiratory symptoms.
Diagnostic bronchoscopy to evaluate airway abnormalities.

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Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation

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Main Results:

The patient presented with severe respiratory complications secondary to rickets.
Bronchoscopy revealed tracheobronchomalacia, a condition affecting the windpipe.
This finding suggests a potential link between rickets and airway instability.

Conclusions:

Tracheobronchomalacia may be an unrecognized complication of rickets.
Further research is needed to confirm and understand this association.
Early recognition and investigation of airway issues in rickets are crucial.