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Updated: May 31, 2026

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
Published on: April 22, 2016
[Succinic acid production using mobile bed of immobilized Actinobacillus succinogenes in alginate]
Roxana Rotaru1, Lenuţa Kloetzer, Anca-Irina Galaction
1Facultatea de Inginerie Chimică si Protecţia Mediului, Departamentul de Inginerie Organică si Biochimică, Universitatea Tehnică Gh. Asachi Iaşi.
Unlabelled:
This work investigates the production of succinic acid by immobilized A. succinogenes cells, using a bioreactor with stirred/mobile bed of biocatalysts.
Material And Method:
The experiments have been carried out for different sizes of biocatalysts particle, under substrate and product inhibitory effects.
Results:
The results indicated that the inhibitory effects could be diminished by cells immobilization, the substrate consumption rate increasing with the increase of biocatalyst particle size. Moreover, the biocatalysts can be used for many fermentation cycles.
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