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Updated: May 31, 2026

A Rat Model of Compound Acne
Published on: November 1, 2024
[Quality-of-life of adolescents with acne vulgaris]
Nermina Kurtalić1, Nermina Hadzigrahić, Husref Tahirović
1Odjel za dermatovenerologiju, Kantonalna bolnica Dr. Irfan Ljubijankić, Bihać, Bosna i Hercegovina.
Objective:
To determine the quality of life in adolescents with acne vulgaris in relation to the severity of clinical picture and sex using the Skindex-29 general questionnaire.
Patients And Methods:
Using a sectional study, the quality of life was analyzed in 90 adolescents of both sexes, aged 16 to 21 years, who were suffering from acne vulgaris. The study was conducted between January 1, 2008 and January 31, 2009, at Department of Dermatovenereology, Dr. Irfan Ljubijankić Cantonal Hospital in Biha6. According to the type of efflorescence, its localization and severity of clinical features, respondents were classified in three groups: group 1 consisted of adolescents with acne comedonica, group 2 with acne papulopustulosa, and group 3 with acne conglobata. The quality of life in these adolescents suffering from acne vulgaris was evaluated by using the general Skindex-29 questionnaire consisting of 30 questions grouped into three scales (scale of emotions, symptom scale, and scale of social and physical functioning) about the psychological impact of acne on the quality of life.
Results:
In the study group, there were 54 (60%) female and 36 (40%) male respondents, mean age 17.5 (range 15.6-20.6) years. Of the total number of patients with acne vulgaris, nine (4 female and 5 male; 10%) had acne comedonica (group 1), 72 (46 female and 26 male; 80%) acne papulopustulosa (group 2) and nine (4 female and 5 male; 10%) acne conglobata (group 3) (p > 0.95). Skindex-29 values expressed as mean +/- SD or median (range) in groups 1,2 and 3 were as follows: on the scale of emotions 43.1 +/- 22.2, 60.4 +/- 20.1 and 52.5 +/- 28.7 (p = 0.084); on the scale of symptoms 26.5 +/- 15.4, 49.0 +/- 20.5 and 42.95 +/- 26.1 (p = 0.039); and on the scale of functioning 23.4 +/- 24.6, 36.0 +/- 23.2 and 34.8 +/- 30.9 (p = 0.341), with cumulative score of 31.0 +/- 10.5, 47.5 +/- 12.0 and 43.44 +/- 8.8 (p = 0.069), respectively. Skindex-29 values were expressed as median (range) in women and men in all three groups, as follows: women, scale of emotions 44.0 (27.5-60), 64.0 (10-90) and 62.5 (5-83) (p = 0.25); scale of symptoms 32.7 (21.5-42.4), 54.2 (17.6-90) and 63.5 (17.8-92) (p = 0.17); scale of functioning 22.2 (2-46.5), 39.2 (0-90) and 51.6 (0-83) (p = 0.31); and men, scale of emotions 30.0 (22.5-90), 55.5 (7.5-100) and 40.2 (30-97.5) (p = 0.26); scale of symptoms 11.9 (4-50), 54.0 (0-75) and 28.5 (17.8-42.8) (p = 0.003); and scale of functioning 13.0 (5-77), 31.7 (0-84) and 14.6 (4.5-72.9) (p = 0.58).
Conclusion:
Acne vulgaris affects the quality of life in adolescents involved regardless of the severity of the clinical picture, with a pronounced impact in women.
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