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Bioecological factors & rotavirus diarrhoea
S Ram1, S Khurana, S B Khurana
1Department of Microbiology, Dayanand Medical College & Hospital, Ludhiana.
The Indian Journal of Medical Research
|May 1, 1990
Summary
Rotavirus infection affects over 11% of young children with diarrhea, with incidence varying by month and negatively correlating with humidity. Boys aged 10-12 months are most susceptible.
Area of Science:
- Pediatrics
- Virology
- Public Health
Background:
- Rotavirus is a leading cause of severe diarrheal disease in infants and young children globally.
- Understanding the epidemiology of rotavirus infection is crucial for developing effective prevention and control strategies.
Purpose of the Study:
- To determine the prevalence of rotavirus infection in children under three years of age presenting with diarrhea.
- To investigate the association of rotavirus infection with demographic factors, seasonality, and environmental conditions.
Main Methods:
- Rotavirus detection was performed using Rotalex assay.
- Group-specific ELISA was employed to identify rotavirus subgroups.
- Statistical analysis was used to assess correlations with environmental factors and demographic data.
Main Results:
- Rotavirus was detected in 11.72% of 1024 children with diarrhea; no rotavirus was found in 25 healthy controls.
- Subgroup analysis revealed 30 cases of subgroup I and 43 of subgroup II, with 10 untypable cases.
- Incidence varied monthly (2.8-22.20%), showed a negative correlation with relative humidity (r = -0.645), and peaked in children aged 10-12 months. Male children were more affected (3.3:1 ratio).
Conclusions:
- Rotavirus is a significant pathogen in young children with diarrhea in the studied population.
- Epidemiological factors such as age, sex, and relative humidity play a role in rotavirus transmission and incidence.