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Published on: September 20, 2018
Anorectal function evaluation and predictive factors for faecal incontinence in 600 patients
T J Lam1, D J Kuik, R J F Felt-Bersma
1Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands. tj.lam@vumc.nl
A predictive model accurately identifies fecal incontinence (FI) in women, utilizing factors like age and anal pressures. This model shows promise for predicting FI, even after stoma closure.
Area of Science:
- Gastroenterology
- Pelvic Floor Disorders
- Surgical Outcomes
Background:
- Faecal incontinence (FI) significantly impacts quality of life.
- Understanding predictive factors for FI is crucial for effective management.
- Anorectal function assessment aids in diagnosing and managing FI.
Purpose of the Study:
- To assess anorectal function in patients with and without faecal incontinence (FI).
- To identify risk factors predictive for FI.
- To develop a statistical model for predicting FI.
Main Methods:
- Consecutive patients underwent assessment via questionnaire, anorectal manometry, and anal endosonography between 2003 and 2009.
- Predictive factors were identified to develop a statistical model for FI prediction.
- The model's accuracy was evaluated, including in patients with temporary stomas.
Main Results:
- Of 600 patients, 48% experienced faecal incontinence.
- Incontinent women were older, had more liquid stools, more deliveries, urinary incontinence, lower anal pressures, shorter sphincter length, smaller rectal capacity, and more sphincter defects.
- The predictive model for FI in women demonstrated an area under the ROC-curve of 0.84, with high sensitivity (86%) and negative predictive value (82%).
Conclusions:
- Incontinent patients exhibit reduced pressures, smaller rectal capacity, and more sphincter defects compared to controls, with considerable overlap.
- The developed model shows high sensitivity and negative predictive value for predicting FI in women.
- The model appears promising for predicting FI in patients with temporary stomas.
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