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Updated: May 31, 2026

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
Published on: June 6, 2018
[Role of miR-145 in erectile dysfunction in diabetic rats]
An-yang Wei1, Yong Yang, Shu-hua He
1Division of Urinary Surgery, Huiqiao Department, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. profway@126.com
Objective:
To investigate the role of miR-145 in the corpus cavernosum smooth muscle tissue in the pathogenesis of erectile dysfunction (ED) in diabetic rats.
Methods:
The total RNA was extracted from the corpus cavernosum of a diabetic rat model with ED, diabetic rats with normal erectile function and normal rats, and the expression levels of miR145 were compared between the groups.
Results:
The expression of miR-145 was decreased in the corpus cavernosum of diabetic rats with ED.
Conclusion:
Diabetes mellitus can cause ED in rats, in which process decreased expression of miR145 in the corpus cavernosum may play a role.
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