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Updated: May 31, 2026

Resurrection of Dormant Daphnia magna: Protocol and Applications
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Published on: January 19, 2018

Evo-devo and accounting for Darwin's endless forms.

Paul M Brakefield1

  • 1Department of Zoology, University Museum of Zoology Cambridge, , University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK. pb499@cam.ac.uk

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|June 22, 2011
PubMed
Summary

Evolutionary developmental biology (evo-devo) explains animal diversity by studying how development generates evolutionary novelty. It highlights the role of ancient gene regulation in shaping life's forms.

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Area of Science:

  • Evolutionary developmental biology (Evo-Devo)
  • Comparative genomics
  • Animal diversification

Background:

  • Evo-devo links developmental processes to evolutionary diversification, explaining the vast array of animal life.
  • It provides insights into the origin of evolutionary novelties and adaptive radiations.
  • Evo-devo supports Darwin's concepts of common ancestry and descent with modification.

Purpose of the Study:

  • To explore how developmental mechanisms contribute to evolutionary patterns.
  • To investigate the role of regulatory gene evolution in generating biological diversity.
  • To examine the potential for developmental constraints in shaping evolutionary trajectories.

Main Methods:

  • Analysis of gene regulatory networks.
  • Comparative studies of developmental pathways across species.
  • Exploration of morphospace and trait-space limitations.

Main Results:

  • Evolution of developmental regulation, rather than new genes, drives the diversity of forms.
  • Evolvability of developmental systems is crucial for generating selectable variation.
  • A balance between 'endless forms' and developmental constraints is increasingly recognized.

Conclusions:

  • Evo-devo provides a framework for understanding evolutionary diversification through developmental processes.
  • The evolution of gene regulation is key to generating biological novelty and diversity.
  • Future research may extend these principles to the evolution of behavior, exploring if 'old genes learn new tricks'.