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Updated: May 31, 2026

Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay
Published on: June 7, 2020
A water-soluble perylene dye functionalised with a 17β-estradiol: a new fluorescent tool for steroid hormones
Francisco J Céspedes-Guirao1, Ana B Ropero, Enrique Font-Sanchis
1División de Química Orgánica, Instituto de Bioingeniería, Universidad Miguel Hernández, Elche 03202, Spain.
Abstract:
We have successfully been able to synthesise a specific estrogen receptor-directed biolabel based on a fluorescent water-soluble perylenebisimide, thus offering great potential for determining the presence of estrogen receptors in any kind of cell. Moreover, this synthetic strategy allows the preparation of other conjugates involved in the study of any kind of receptor, simply by selecting the appropriate agonist or antagonist.
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