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Updated: May 31, 2026
13:53
Homogeneous Glycoconjugate Produced by Combined Unnatural Amino Acid Incorporation and Click-Chemistry for Vaccine Purposes
Published on: December 19, 2020
[Quadrivalent meningococcal conjugate vaccine].
1Centre de vaccinations et médecine des voyages, PMU, 1011 Lausanne. Pierre.Landry@hospvd.ch
Revue Medicale Suisse
|June 23, 2011
Summary
Meningococcal meningitis remains a serious illness. New quadrivalent ACWY vaccines offer improved protection and may simplify vaccination schedules for travelers and at-risk children.
Area of Science:
- Epidemiology of infectious diseases.
- Vaccinology and immunology.
- Public health and preventive medicine.
Context:
- Meningococcal meningitis is a severe bacterial infection with significant public health implications.
- Current vaccination recommendations in Switzerland primarily address serotypes B and C.
- Global epidemiology of meningococcal serotypes is dynamic, with potential shifts in predominant strains.
Purpose:
- To review current Swiss immunization guidelines for meningococcal infections.
- To introduce new quadrivalent protein-conjugated vaccines effective against serogroups ACWY.
- To evaluate the advantages of these novel vaccines for disease prevention.
Summary:
- New quadrivalent meningococcal vaccines targeting serogroups ACWY are becoming available in Switzerland.
- These vaccines offer broader serogroup coverage compared to existing options.
- They are expected to simplify vaccination schedules and enhance protection, particularly for specific populations.
Impact:
- Improved public health outcomes through enhanced prevention of meningococcal disease.
- Simplified vaccination strategies for healthcare providers and the public.
- Increased protection for travelers and children at risk of severe meningococcal complications.
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