Related Experiment Video
Updated: May 31, 2026
07:30
Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Ultrasensitive DNA detection based on Au nanoparticles and isothermal circular double-assisted
Hong Zhou1, Jing Liu, Jing-Juan Xu
1Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, PR China.
Chemical Communications (Cambridge, England)
|June 23, 2011
Abstract:
We report here an ultrasensitive DNA detection approach which combines Au NPs enhanced electrochemiluminescence (ECL) of the CdS nanocrystal (NC) film with isothermal circular amplification reaction of polymerase and nicking endonuclease (NEase). By the double-signal amplification, this approach could sensitively respond down to 5 aM DNA.
