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Local giant cell foreign body reaction after silicone injection for fecal incontinence in humans: two case reports
B van Wunnik1, A Driessen, C Baeten
1Department of Surgery, Maastricht University Medical Centre, P. Debyelaan 25, 6202 AZ, Maastricht, The Netherlands. b.van.wunnik@mumc.nl
Techniques in Coloproctology
|June 23, 2011
Abstract:
Since the 1990s, one of the methods used for treating fecal incontinence due to internal anal sphincter defects has been the injection of bulking agents. The aim of this paper is to report two cases of local giant cell foreign body reaction after injection of PTQ(TM) in humans. To the best of the authors' knowledge, this is the first report of an adverse immune response to silicone injection in humans.
