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Related Experiment Videos

Athlete's foot.

Fay Crawford¹

¹University of Edinburgh, Edinburgh, UK.

BMJ Clinical Evidence

|June 24, 2011

Summary

This summary is machine-generated.

Athlete's foot affects 15-25% of people. This review examines topical treatments like allylamines, azoles, and ciclopirox olamine for effectiveness and safety.

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Area of Science:

Dermatology
Pharmacology
Evidence-Based Medicine

Background:

Athlete's foot (tinea pedis) is a common fungal infection affecting 15-25% of the population.
The infection is contagious and can spread to other body parts and individuals.

Purpose of the Study:

To systematically review the clinical effectiveness and safety of various topical treatments for athlete's foot.
To evaluate interventions including improved foot hygiene and specific antifungal medications.

Main Methods:

A systematic literature search was conducted across major databases (Medline, Embase, Cochrane Library) up to July 2008.
Included studies comprised systematic reviews, randomized controlled trials (RCTs), and observational studies.
Harms alerts from regulatory agencies (FDA, MHRA) were also incorporated.

Main Results:

Fourteen systematic reviews, RCTs, or observational studies met the inclusion criteria.
A GRADE evaluation was performed to assess the quality of evidence for each intervention.

Conclusions:

The review presents data on the effectiveness and safety of topical treatments for athlete's foot.
Interventions analyzed include foot hygiene, topical allylamines (naftifine, terbinafine), topical azoles (bifonazole, clotrimazole, econazole, miconazole, sulconazole, tioconazole), and ciclopirox olamine.