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Updated: May 31, 2026
09:03
Trypsin Digest Protocol to Analyze the Retinal Vasculature of a Mouse Model
Published on: June 13, 2013
[New treatments for diabetic retinopathy]
1Service d'ophtalmologie, hôpital Lariboisière, AP-HP, université Paris 7, 2, rue Ambroise-Paré, 75475 Paris cedex 10, France. p.massin@lrb.aphp.fr
Journal Francais D'Ophtalmologie
|June 24, 2011
Summary
Diabetic retinopathy lacks preventative drugs, but treatments for complications like diabetic macular edema show promise. Ranibizumab and intravitreal triamcinolone acetonide improve vision but have drawbacks.
Area of Science:
- Ophthalmology and Endocrinology
- Diabetic retinopathy research
- Vascular complications of diabetes
Context:
- Despite glycemic and blood pressure control reducing diabetic retinopathy (DR) incidence and progression, no preventative drugs exist.
- Significant advancements have been made in managing DR complications, particularly diabetic macular edema (DME).
Purpose:
- To review current therapeutic strategies for diabetic macular edema.
- To evaluate the efficacy and limitations of available treatments for DME.
Summary:
- Ranibizumab is an approved treatment for DME, improving visual acuity but requiring repeated intravitreal injections and monthly monitoring.
- Intravitreal triamcinolone acetonide also reduces macular edema and enhances visual acuity, but carries significant side effects and lacks marketing authorization for intraocular use.
- Triamcinolone acetonide is typically reserved for cases failing or intolerant to anti-VEGF therapy or laser treatment.
Impact:
- Current treatments for DME offer visual improvement but necessitate burdensome treatment regimens and carry risks.
- Further research is needed for preventative strategies and safer, more effective treatments for diabetic retinopathy and its complications.
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