Recurrent corneal hypertrophic scar after laser-assisted subepithelial keratectomy with mitomycin C treatment
Related Experiment Video
Updated: May 31, 2026
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Jae-Hyung Kim1, Myoung Joon Kim, Dong Yoon Kim
1Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Purpose:
To report recurrent corneal hypertrophic scar after laser-assisted subepithelial keratectomy (LASEK) with mitomycin C treatment.
Methods:
Two patients experienced decreased visual acuity in 1 eye arising from elevated corneal opacity about 12 months after uneventful LASEK with intraoperative mitomycin C application. The elevated opacities were easily removed mechanically.
Results:
Pathologic examinations showed irregular arrangement of collagen fibers and myofibroblasts, diagnosed as hypertrophic scars. The lesions recurred at about 4-month intervals, despite repeated debridement with and without prophylactic mitomycin C treatment.
Conclusions:
Recurrent corneal hypertrophic scar may be a rare complication after LASEK treatment with mitomycin C application.
