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Related Experiment Video

Updated: May 31, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

Physical activity, sedentary behavior, and melatonin among rotating shift nurses.

Mark McPherson¹, Ian Janssen, Anne Grundy

¹Department of Community Health and Epidemiology, Queen's University, Kingston, Ontario, Canada.

Journal of Occupational and Environmental Medicine

|June 24, 2011

Summary

Physical activity and sedentary behavior inversely affect melatonin levels in rotating shift nurses. Higher energy expenditure during the day shift and sedentary behavior during the night shift were linked to lower melatonin concentrations.

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Area of Science:

Chronobiology
Occupational Health
Endocrinology

Background:

Rotating shift work disrupts circadian rhythms and sleep patterns.
Melatonin, a key hormone regulating sleep-wake cycles, is sensitive to light and activity.
Understanding the impact of lifestyle factors on melatonin is crucial for shift workers' health.

Purpose of the Study:

To investigate the relationship between physical activity, sedentary behavior, and urinary melatonin levels in rotating shift nurses.
To differentiate the effects during day and night shifts.

Main Methods:

118 nurses recorded physical activity and sedentary behaviors using diaries over day and night shifts.
Urinary 6-sulfatoxymelatonin concentrations were measured for each shift.

Main Results:

During day shifts, moderate-to-vigorous physical activity between 3 PM and 7 AM showed a negative association with melatonin levels (P=0.024).
During night shifts, sedentary behavior was negatively associated with melatonin levels (P=0.008).

Conclusions:

Both physical activity and sedentary behavior are inversely associated with morning melatonin levels in shift nurses.
These behaviors explain a small portion of melatonin variation, suggesting limited impact on peak melatonin levels.