Related Experiment Video

Updated: May 31, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
05:25

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft

Published on: September 15, 2023

Coronary artery bypass grafting for acute myocardial infarction in stent ERA

Tamaki Takano1, Hirohisa Goto, Kazuo Hoshino

  • 1Department of Cardiac Surgery and Cardiology, Cardiovascular Center, Shinonoi General Hospital, Nagano, Nagano, Japan. ttakano-ths@umin.ac.jp

Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
|June 24, 2011
PubMed

Insights

This study found no in-hospital mortality in acute myocardial infarction (AMI) patients treated with a strategy involving percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). Preceding PCI did not significantly impact outcomes compared to no PCI.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Acute myocardial infarction (AMI) management requires timely and effective interventions.
  • Treatment strategies aim to minimize mortality and complications.
  • The role of percutaneous coronary intervention (PCI) prior to coronary artery bypass grafting (CABG) in specific AMI cases warrants investigation.

Purpose of the Study:

  • To evaluate a treatment strategy for AMI involving PCI for culprit lesions, excluding unprotected left main trunk.
  • To assess emergent CABG for left main trunk culprits with mechanical complications.
  • To compare outcomes between AMI patients undergoing CABG with and without preceding PCI.

Main Methods:

  • Retrospective analysis of 22 AMI patients undergoing CABG from 1997-2008.
  • Comparison with 232 non-AMI patients undergoing CABG.
  • Assessment of complication rates, intubation periods, in-hospital mortality, and hospitalization duration.
  • Subgroup analysis of AMI patients based on preceding PCI.

Main Results:

  • No in-hospital mortality observed in the 22 AMI patients.
  • No significant difference in in-hospital mortality or complications between AMI and non-AMI CABG groups.
  • Preceding PCI in AMI patients showed no significant difference in hospital stay, complications, intubation, or mortality compared to those without preceding PCI.

Conclusions:

  • The evaluated treatment strategy for AMI is deemed reasonable.
  • Further research is needed to fully elucidate the role of preceding PCI in AMI management.
  • Outcomes suggest a potentially safe and effective approach to AMI involving PCI and CABG.
Abstract

More Related Videos

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery09:12

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Published on: March 27, 2018

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

Published on: April 24, 2017

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...