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Infection of pacemaker lead by penicillin-resistant Streptococcus Pneumoniae

Hideki Morita1, Yoshio Misawa, Shinichi Oki

  • 1Division of Cardiovascular Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan. udon@jichi.ac.jp

Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
|June 24, 2011
PubMed

Insights

Penicillin-resistant Streptococcus pneumoniae (PRSP) infections are rising globally. This case study details successfully treating a pacemaker lead infection caused by PRSP using vancomycin and lead extraction.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Medical Device Infections

Background:

  • Penicillin-resistant Streptococcus pneumoniae (PRSP) represents a growing global health concern.
  • Infections associated with permanent pacemakers are infrequent but serious complications.
  • Limited reports exist on PRSP specifically causing pacemaker lead infections.

Observation:

  • A patient experienced recurrent endocarditis and sepsis attributed to PRSP.
  • The infection originated from the pacemaker lead within the right atrium.
  • The patient suffered seven distinct episodes of infection.

Findings:

  • Successful resolution of a challenging PRSP pacemaker lead infection was achieved.
  • Treatment involved a combination of periodic vancomycin administration and complete pacemaker lead extraction.
  • This approach effectively eradicated the persistent infection.

Implications:

  • Highlights the potential for PRSP to cause severe pacemaker lead infections.
  • Demonstrates the efficacy of vancomycin and lead extraction in managing such infections.
  • Suggests a treatment paradigm for similar complex device-related infections.

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