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[Endoscopic treatment of vesicoureteral reflux in children]

S Ionescu1, S Tîrlea

  • 1U.M.E Carol Davila, Clinica de Chirurgie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii M.S. Curie, Bucureşti.

Chirurgia (Bucharest, Romania : 1990)
|June 25, 2011
PubMed

Insights

Endoscopic subureteral injection effectively treats vesicoureteral reflux (VUR) in children, achieving high success rates with minimal complications. This minimally invasive approach offers a safe and efficient alternative for managing VUR across all grades.

Area of Science:

  • Pediatric Urology
  • Minimally Invasive Surgery
  • Urologic Oncology

Context:

  • Vesicoureteral reflux (VUR) is a common condition in children with varying management approaches.
  • Consensus guidelines exist, but endoscopic treatment offers an efficient alternative.
  • This study evaluates endoscopic subureteral injection for VUR management.

Purpose:

  • To assess the efficacy and safety of endoscopic subureteral injection using dextranomer/hyaluronic acid for treating VUR in pediatric patients.
  • To determine the success rate and complication profile of this minimally invasive procedure.

Summary:

  • 58 children with VUR (grades II-V) underwent endoscopic subureteral injection of dextranomer/hyaluronic acid (Deflux).
  • The study included 95 ureters, with reflux classified by grade.
  • Follow-up involved micturitional cystography and ultrasound.

Impact:

  • Endoscopic treatment achieved high remission rates: 66.31% after the first injection, 13.68% after the second, and 1.05% after the third.
  • The procedure demonstrated significant advantages, including a high success rate, absence of postoperative complications, and reduced hospitalization.
  • Endoscopic subureteral injection is indicated for all grades of VUR, offering a safe and effective treatment option.
Abstract

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