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Electro-acupuncture can alleviate the cerebral oedema of rat after ischemia
1Department of Rehabilitation, Huashan Hospital, Fudan University, WuLuMuQi Middle Road 12, Shanghai, PR China.
Primary Objective:
This study was designed to determine whether electro-acupuncture (EA) could alleviate cerebral oedema after cerebral ischemia.
Research Design:
EA has been widely used for cerebrovascular disease in East Asian countries. However, whether EA might reduce cerebral oedema after stroke remains unclear. In the current study, diffusion-weighted MRI, which is a reliable method for detecting cerebral oedema, was used to determine whether EA could ameliorate cerebral oedema.
Methods And Procedures:
Twelve rats with induced strokes were divided into two groups: one group with EA treatment (EA group) and one group without EA treatment (non-EA group). Both groups of rats underwent MRI scanning at the same time point following ischemia.
Main Outcomes And Results:
Diffusion-weighted imaging showed that the relative apparent diffusion coefficient increased significantly in the cortical and sub-cortical areas of the EA group relative to the non-EA group, indicating that EA can alleviate cerebral oedema after ischemic stroke.
Conclusions:
Electro-acupuncture can alleviate cerebral oedema in rats following ischemia.