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Updated: May 31, 2026

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

Polymeric nanofibers in tissue engineering.

Rebecca L Dahlin1, F Kurtis Kasper, Antonios G Mikos

  • 1Department of Bioengineering, Rice University, Houston, Texas 77251-1892, USA.

Tissue Engineering. Part B, Reviews
|June 25, 2011
PubMed
Summary
This summary is machine-generated.

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Polymeric nanofibers offer tunable properties for tissue engineering. This review covers their fabrication, characterization, and applications in regenerating bone, cartilage, and other tissues.

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Nanotechnology

Background:

  • Polymeric nanofibers mimic natural extracellular matrix (ECM) due to their small diameter and high surface area.
  • These properties are advantageous for cell attachment, bioactive factor delivery, and tissue regeneration.
  • Current fabrication methods allow for precise control over nanofiber characteristics.

Purpose of the Study:

  • To review nanofiber fabrication and characterization techniques relevant to tissue engineering.
  • To discuss the integration of bioactive factors within nanofiber scaffolds.
  • To explore the applications of polymeric nanofibers in various tissue engineering fields.

Main Methods:

  • Electrospinning, phase separation, and self-assembly are key nanofiber production methods.

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Last Updated: May 31, 2026

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

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  • Characterization focuses on fiber composition, diameter, alignment, porosity, and degradation.
  • Methods for incorporating and controlling the release of bioactive factors are examined.

    • Main Results:

    • Nanofiber properties can be tailored for specific tissue engineering applications.
    • Controlled porous structures and degradation rates enhance cell infiltration and tissue integration.
    • Successful loading and delivery of bioactive factors are crucial for therapeutic efficacy.

    Conclusions:

    • Polymeric nanofibers are versatile scaffolds for diverse tissue engineering applications.
    • Optimization of fabrication and characterization is essential for successful clinical translation.
    • Future research should focus on advanced nanofiber designs for complex regenerative challenges.