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Consequence of masked hypertension in treated hypertensive outpatients: 1-year follow-up study

Yuko Ohta1, Takuya Tsuchihashi, Kanako Kiyohara

  • 1Division of Hypertension, Clinical Research Institute, National Kyushu Medical Center, Fukuoka, Japan. yukoo@kyumed.jp

Clinical and Experimental Hypertension (New York, N.Y. : 1993)
|June 25, 2011
PubMed

Insights

Masked hypertension (MHT) affects treated hypertensive patients, with one-third improving home blood pressure (HBP) control after one year. Lifestyle changes and medication adjustments are key for managing MHT and reducing cardiovascular risk.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Public Health

Background:

  • Masked hypertension (MHT) poses a significant cardiovascular disease risk.
  • Effective home blood pressure (HBP) control is crucial for managing hypertension.
  • Understanding MHT prevalence and outcomes in treated patients is essential.

Purpose of the Study:

  • To determine the prevalence of masked hypertension (MHT) in treated hypertensive outpatients.
  • To evaluate the impact of a 1-year follow-up on blood pressure (BP) control status.
  • To identify factors influencing BP control and MHT status.

Main Methods:

  • A cohort of 262 treated hypertensive outpatients was studied over one year (2008-2009).
  • Clinic BP (CBP) and morning home BP (HBP) were measured.
  • Background characteristics, antihypertensive drug regimens, and lifestyle factors were assessed.

Main Results:

  • Clinic BP and morning HBP significantly decreased after one year (p < 0.01).
  • Sustained hypertension decreased from 17.9% to 6.9%; 34% of these became MHT or normotensive (NT).
  • Among MHT patients, 62% remained MHT, while 32.9% became NT. Sustained MHT was linked to male gender and alcohol intake. Nighttime dosing and diuretics improved morning HBP.

Conclusions:

  • Approximately one-third of masked hypertension (MHT) patients achieved improved home blood pressure (HBP) control within a year.
  • Intensive antihypertensive treatment, including diuretics and lifestyle modifications like alcohol restriction, is vital for MHT management.
  • Effective management of MHT is critical for mitigating cardiovascular disease risk in treated hypertensive populations.

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