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Updated: May 31, 2026

2-Vessel Occlusion/Hypotension: A Rat Model of Global Brain Ischemia
Published on: June 22, 2013
Hippocampus: a "forgotten" border zone of brain ischemia
Kamel Walha1, Fréderic Ricolfi, Yannick Béjot
1Department of Neuroradiology, University Hospital of Dijon, 21033 Dijon Cedex, France.
Background:
Hippocampus is selectively susceptible to ischemic damage and it could be, in some conditions, considered as a border zone of brain ischemia.
Results:
We illustrate this concept with three cases of hippocampal diffusion-weighted imaging (DWI) restrictions secondary to a carotid artery dissection with an ipsilateral fetal posterior cerebral artery (PCA) in two cases and to global brain hypoperfusion consequent to a cardiac arrest in the last case.
Conclusion:
The hypoperfusion induced by a cardiac arrest or an internal carotid dissection with an incomplete circle of Willis promotes hippocampal ischemia in the territories of the anterior choroidal artery and the longitudinal terminal segments of the hippocampal arteries.
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