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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

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Related Experiment Video

Updated: May 31, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Traumatic cataract associated with mini glaucoma shunt.

Jennifer Y Li1, Michele C Lim, Mark J Mannis

  • 1UC Davis Health System Eye Center, University of California at Davis, Sacramento, California, USA.

Journal of Cataract and Refractive Surgery
|June 25, 2011
PubMed
Summary

A 30-year-old woman with aniridia experienced a traumatic cataract after Ex-PRESS mini glaucoma shunt surgery. This case highlights a potential, previously unreported complication of this glaucoma device.

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Published on: February 15, 2022

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Published on: December 1, 2023

Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Cataract Development

Background:

  • Aniridia is a rare genetic disorder affecting iris development.
  • Glaucoma shunts, like the Ex-PRESS mini glaucoma shunt, are used to manage intraocular pressure.
  • Cataract formation is a known risk following ocular surgery.

Observation:

  • A 30-year-old female patient with a history of aniridia presented with vision changes.
  • The patient had recently undergone implantation of an Ex-PRESS mini glaucoma shunt.
  • Ocular examination revealed a traumatic cataract.

Findings:

  • The development of a traumatic cataract was directly associated with the Ex-PRESS mini glaucoma shunt placement.
  • This represents a potential complication of Ex-PRESS mini glaucoma shunt surgery.
  • No prior reports document this specific complication.

Implications:

  • Ophthalmologists should be aware of the risk of traumatic cataract formation after Ex-PRESS mini glaucoma shunt implantation in patients with aniridia.
  • Further investigation may be warranted to understand the mechanism of this complication.
  • This finding may influence surgical decision-making and patient counseling for glaucoma management in aniridia patients.