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[Candidiasis, aspergillosis and other invasive mycoses in recipients of solid organ transplants]

Guillermo Quindós1

  • 1Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco-Euskal Herriko Unibertsitatea, Bilbao, Vizcaya, España. guillermo.quindos@ehu.es

Revista Iberoamericana De Micologia
|June 25, 2011
PubMed

Insights

Invasive fungal diseases (IFD) remain a significant threat to solid organ transplant recipients. This review updates knowledge on IFD epidemiology, diagnosis, and treatment, focusing on invasive aspergillosis and candidiasis.

Area of Science:

  • Mycology
  • Transplant Medicine
  • Infectious Diseases

Context:

  • Invasive fungal diseases (IFD) significantly contribute to morbidity and mortality in solid organ transplant (SOT) recipients.
  • Advances in surgical procedures, supportive care, and antifungal therapies have altered IFD epidemiology and outcomes.

Purpose:

  • To provide an updated review of the current literature on the epidemiology, diagnosis, and treatment of IFD in SOT recipients.
  • To highlight key findings concerning invasive aspergillosis and candidiasis, the most common IFDs in this population.

Summary:

  • Candida and other yeasts remain significant pathogens, while Aspergillus and other filamentous fungi are predominant in lung transplant recipients.
  • The review synthesizes recent research on diagnostic strategies and therapeutic interventions for IFD in SOT patients.
  • Evolving trends in IFD incidence and clinical presentation are discussed in light of improved transplant care.

Impact:

  • Informs clinicians and researchers on the current landscape of IFD in SOT, aiding in improved patient management.
  • Facilitates evidence-based decision-making for the prevention, diagnosis, and treatment of IFD.
  • Contributes to reducing the burden of IFD-related complications in the growing population of SOT recipients.

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