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Manual Segmentation of the Human Choroid Plexus Using Brain MRI
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Manual Segmentation of the Human Choroid Plexus Using Brain MRI

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Hydrocephalus due to diffuse villous hyperplasia of the choroid plexus

Ryogo Anei1, Yoshimitsu Hayashi, Satoru Hiroshima

  • 1Department of Neurosurgery, Asahikawa Medical College, Hokkaido, Japan. anei@asahikawa-med.ac.jp

Neurologia Medico-Chirurgica
|June 25, 2011
PubMed

Insights

This study details a rare case of infant hydrocephalus caused by excessive cerebrospinal fluid (CSF) overproduction. A ventriculoatrial shunt effectively managed the condition after other methods failed.

Area of Science:

  • Pediatric Neurology
  • Neurosurgery
  • Medical Imaging

Background:

  • Hydrocephalus in infants can result from cerebrospinal fluid (CSF) overproduction.
  • Distinguishing between choroid plexus hyperplasia and papilloma can be clinically challenging.
  • Initial management with ventriculoperitoneal shunts may lead to complications like ascites.

Observation:

  • An 8-month-old female presented with hydrocephalus due to bilateral choroid plexus enlargement.
  • Imaging studies showed symmetric enhancement of choroid plexuses, with Thallium-201 SPECT indicating high uptake and washout.
  • Cerebrospinal fluid analysis ruled out atypical cells.

Findings:

  • The patient exhibited excessive CSF production (1,500 ml/day).
  • Despite initial shunt surgery, ascites developed, necessitating external drainage.
  • A ventriculoatrial shunt provided effective hydrocephalus control.

Implications:

  • This case highlights the importance of considering diverse etiologies for pediatric hydrocephalus.
  • Advanced imaging and nuclear medicine techniques aid in diagnosis and management.
  • Alternative surgical approaches, such as ventriculoatrial shunting, are crucial when complications arise.

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