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Measuring Psoriasis Severity at Home
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Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Patients with psoriasis have a higher prevalence of parental cardiovascular disease

Paolo Gisondi1, Camilla Dalle Vedove, Giampiero Girolomoni

  • 1Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy. paolo.gisondi@univr.it

Dermatology (Basel, Switzerland)
|June 25, 2011
PubMed

Insights

Patients with psoriasis have a higher prevalence of parental cardiovascular disease (CVD) history, including maternal myocardial infarction and paternal stroke. This suggests assessing family history of CVD in psoriasis patients can improve cardiovascular risk assessment.

Area of Science:

  • Cardiology
  • Dermatology
  • Genetics

Background:

  • Parental history of cardiovascular disease (CVD) is a significant risk factor for offspring CVD.
  • Patients with chronic plaque psoriasis face an intermediate risk of developing CVD.

Purpose of the Study:

  • To determine the prevalence of a parental history of CVD among individuals with psoriasis.
  • To assess the association between psoriasis and parental history of myocardial infarction and stroke.

Main Methods:

  • A cross-sectional study involving 236 adult patients with chronic plaque psoriasis and 246 controls.
  • Parental history of myocardial infarction and/or stroke was gathered using a structured questionnaire.
  • Self-reported data accuracy was verified against hospital records.

Main Results:

  • A significantly higher prevalence of positive parental history of maternal myocardial infarction (11.8% vs. 6.5%) and premature maternal myocardial infarction (6.8% vs. 1.2%) was observed in psoriasis patients.
  • Psoriasis patients also showed a higher incidence of positive parental history of paternal stroke (10.5% vs. 5.6%).
  • A parental history of psoriasis was notably more common in cases (35%) than controls (2%).

Conclusions:

  • Parental history of CVD is more prevalent in patients with psoriasis.
  • Investigating parental history of CVD in psoriasis patients is recommended for a thorough cardiovascular risk evaluation.
Abstract

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