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Feeding very-low-birth-weight infants: our aspirations versus the reality in practice
Willemijn E Corpeleijn1, Marijn J Vermeulen, Chris H van den Akker
1Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
Insights
Optimizing nutrition for premature infants is crucial, as deficits can lead to serious health issues. This review highlights key strategies for improving nutritional intake in the neonatal intensive care unit.
Area of Science:
- Neonatal nutrition
- Pediatric gastroenterology
Background:
- New guidelines for enteral nutrition in premature infants exist.
- Achieving recommended intakes remains challenging in neonatal intensive care units, risking nutritional deficits.
- Suboptimal intake is linked to neonatal diseases and impaired neurodevelopment.
Purpose of the Study:
- To review essential aspects for optimizing nutritional intake in premature infants.
- To emphasize the critical need for improved nutritional support in neonatal intensive care.
Main Methods:
- Literature review of current practices and guidelines for infant nutrition.
- Discussion of infrastructure, parenteral nutrition initiation, and enteral feeding transitions.
- Examination of nutritional tolerance monitoring and macronutrient optimization.
Main Results:
- Optimizing nutrition requires attention to infrastructure, parenteral to enteral feeding transitions, and monitoring.
- Current monitoring methods like serum biochemistry lack specific markers and safety values.
- Unanswered questions persist regarding optimal macronutrient quantity and quality.
Conclusions:
- Premature birth constitutes a nutritional emergency requiring dedicated clinical and research efforts.
- Reducing nutritional deficits is paramount to prevent adverse neonatal outcomes, including neurodevelopmental impairment.
- A hospital-wide acknowledgment of nutritional needs is essential for vulnerable preterm infants.
Abstract:
Recently, new guidelines for enteral feedings in premature infants were issued by the European Society of Pediatric Gastroenterology, Hepatology, and Nutrition Committee on Nutrition. Nevertheless, practice proves difficult to attain suggested intakes at all times, and occurrence of significant potential cumulative nutritional deficits 'lies in wait' in the neonatal intensive care unit. This review describes several aspects that are mandatory for optimizing nutritional intake in these vulnerable infants. These aspects range from optimal infrastructure to the initiation of parenteral nutrition with proper transition to enteral breast or formula feedings. Proper monitoring of nutritional tolerance includes serum biochemistry although proper specific markers are unknown and safety reference values are lacking. Although a lot of progress has been made through research during the last few decades, numerous questions still remain unanswered as to what would be the optimal quantity and quality of the various macronutrients. The inevitable suboptimal intake may, however, contribute significantly to the incidence of neonatal diseases, including impaired neurodevelopment. Therefore, it is pivotal that all hospital staff acknowledges that preterm birth is a nutritional emergency and that all must be done, both in clinical practice as well as in research, to reduce nutritional deficits.
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