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Updated: May 31, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

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Published on: November 2, 2018

High-resolution X-ray structure of the trimeric Scar/WAVE-complex precursor Brk1

Joern Linkner1, Gregor Witte, Theresia Stradal

  • 1Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.

Plos One
|June 25, 2011
PubMed
Summary

The Brk1 trimer from Dictyostelium, a key component of the Scar/WAVE-complex, dissociates at low concentrations. Its structure reveals similarities to human complexes, highlighting its crucial role in Scar/WAVE assembly for cell migration.

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