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Updated: May 31, 2026

08:54
Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
Published on: February 17, 2023
Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor
Marc Vendrell1, Gaddamanugu Gopi Krishna, Krishna Kanta Ghosh
1Laboratory of Bioimaging Probe Development, Singapore Bioimaging Consortium, Agency for Science, Technology and Research, Singapore.
Abstract:
The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.

