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Related Experiment Video

Updated: May 31, 2026

Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers
07:18

Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers

Published on: January 9, 2026

Small gut atresia in neonates.

Arshad Kamal1, Kifayat Khan, Inayat ur Rahman

  • 1Department of Paediatric Surgery, Lady Reading Hospital, Peshawar, Pakistan. arshad_kamal007@yahoo.com

Journal of Ayub Medical College, Abbottabad : JAMC
|June 28, 2011
PubMed
Summary

Small gut atresia is a common neonatal surgical issue. Financial constraints, late presentation, sepsis, and gut complications significantly contribute to mortality and morbidity in affected neonates.

Area of Science:

  • Neonatal surgery
  • Pediatric surgery
  • Gastrointestinal surgery

Background:

  • Small gut atresia is a frequent surgical challenge in newborns.
  • Timely diagnosis and management are crucial for reducing mortality and morbidity.
  • This study investigated the factors contributing to poor outcomes in neonates with small gut atresia.

Purpose of the Study:

  • To identify the primary causes of mortality and morbidity in neonates diagnosed with small gut atresia.
  • To analyze the demographic and clinical characteristics of affected neonates.
  • To evaluate the impact of various factors on patient outcomes.

Main Methods:

  • A prospective study was conducted from August 2007 to August 2009 at Lady Reading Hospital, Peshawar.
  • Included were 40 neonates with small gut atresia; neonates with other causes of intestinal obstruction were excluded.

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  • Diagnosis was often peroperative, distinguishing it from conditions like meconium ileus.

    • Main Results:

    • Type-III(a) atresia was the most common type (50%).
    • Resection and anastomosis were performed in 31 cases; 9 neonates required ileostomy.
    • Key factors contributing to mortality included financial constraints, delayed presentation, aspiration, sepsis, gut perforation, and gangrene.

    Conclusions:

    • Neonates with small gut atresia require specialized care at equipped centers.
    • Multifaceted management strategies are essential to improve survival rates.
    • Addressing socioeconomic factors and ensuring timely surgical intervention are critical.