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Connection between noise-induced symmetry breaking and an information-decoding function for intracellular networks.
1Institute of Industrial Science, The University of Tokyo, Tokyo, Japan. tetsuya@mail.crmind.net
Physical Review Letters
|June 28, 2011
Summary
Noise-induced symmetry breaking (NISB) may help cells decode information from noisy signals. This study reveals NISB
Area of Science:
- Cellular dynamics
- Systems biology
- Biophysics
Background:
- The biological role of noise-induced symmetry breaking (NISB) in intracellular systems remains poorly understood.
- NISB is a phenomenon observed in systems influenced by random fluctuations.
Purpose of the Study:
- To investigate the potential biological function of NISB.
- To explore the link between NISB and information processing in cellular networks.
Main Methods:
- Theoretical analysis of information decoding dynamics.
- Identification of intracellular networks exhibiting NISB.
- Proposal of mean first passage time profiles for experimental validation.
Main Results:
- Information decoding from noisy signals is identified as a potential biological function of NISB.
- NISB naturally emerges from optimal information-decoding dynamics.
- Several intracellular networks align with these information-decoding dynamics.
Conclusions:
- NISB likely plays a crucial role in cellular information processing.
- The findings provide a framework for understanding NISB in biological contexts.
- Mean first passage time profiles offer a method for experimental verification of NISB.
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